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Healing & Recoverypreclinical

BPC-157

Body Protection Compound 157
Healing & Recovery · CAS 137525-51-0
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Category
Healing & Recovery
Evidence grade
D
PubMed records
211
Female-tagged
21
Sex-analysis
0
CAS
137525-51-0
D
Evidence grade D, Preclinical / animal evidence only across 211 indexed studies. No human trial data. How grades work →
Female evidence: None
BPC-157: of 211 PubMed records, 21 are tagged as including female subjects and 0 carry a sex-analysis tag.Counts reflect PubMed records as of 2026-07-17. “Female” uses the Female MeSH filter and “sex-analysis” the Sex Factors MeSH filter, automated proxies pending manual study-level review. Methodology →

Overview

BPC-157 is a synthetic pentadecapeptide, a 15-amino-acid chain derived from a protein sequence found in gastric juice. It has become one of the most widely discussed compounds in the tissue-repair research conversation, and its stability and solubility have made it a common material in laboratory work on healing and cytoprotection.

In preclinical models, BPC-157 has been studied for its relationship to angiogenesis, growth-factor signaling, and the nitric-oxide system, most often in rodent tissue-injury protocols involving tendon, muscle, and gut. Researchers examining wound-healing mechanisms and gastrointestinal protection have returned to it repeatedly as a reference compound, which is part of why popular interest has run so far ahead of the clinical record.

That gap is the honest headline. Despite the volume of preclinical attention, controlled human trials have not been indexed, and the female-specific record is thinner still. For a catalog written around sex-disaggregated evidence, BPC-157 is a clear example of why the question of how many studies included women matters, because the mechanism data is real and the female data is essentially absent.

Summary

BPC-157 is a synthetic pentadecapeptide widely discussed for tissue healing. Despite heavy popular interest, the evidence base is almost entirely preclinical rodent studies, and no controlled human trials have been indexed, a gap that is even wider for female subjects.

Evidence in women

Menstrual cycle
Unstudied
No studies examine menstrual cycle interactions.
Pregnancy & lactation
Unstudied
No pregnancy or lactation safety data exist. Absence of harm data is not evidence of safety.
Hormonal interactions
Unstudied
No data on estrogen, thyroid, or contraceptive interactions.
Perimenopause & menopause
Unstudied
No data in perimenopausal or menopausal populations.
Sex differences
Unstudied
In the indexed literature, small number using female animals reported no sex-stratified outcomes. Any dosing figure circulating online is extrapolated from male-animal data.

Mechanism

Proposed to promote angiogenesis and modulate the nitric-oxide system and growth-factor signaling; mechanisms characterized in rodent tissue-injury models.

Reported dosing & routes

◐

We don't give dosing or medical advice. The figures below describe what was used in published research, not a recommendation. Decide with your clinician.

Reported range (literature)Reported in animal studies only; no established human dose.
Routessubcutaneous, oral, intramuscular
Female-specific dosingNot established

Contraindications: active malignancy (theoretical, due to angiogenic activity)

Side effects

Reported in the research literature. Sex-specific incidence has not been separately analysed in the available records.

insufficient human data to characterize

BPC-157 reconstitution calculator

Enter this vial's amount, the bacteriostatic water you add, and a target amount to get the concentration and the U-100 syringe units to draw. Handling arithmetic for research use, not a dose recommendation.

Reconstitution

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Draw for BPC-157

5
units on a U-100 insulin syringe
020406080100
U-100 insulin syringe — 1 mL = 100 units
That's 0.05 mL drawn to the 5-unit mark.
Concentration5 mg/mL (5,000 mcg/mL)
Volume to draw0.05 mL
Doses per vial40

Reference chart at 5 mg/mL

Target amountVolume (mL)U-100 units
100 mcg0.02 mL2
250 mcg0.05 mL5
500 mcg0.1 mL10
750 mcg0.15 mL15
1000 mcg0.2 mL20

Research-use arithmetic only. This tool converts a vial amount, diluent volume, and a target amount into a concentration and syringe draw for laboratory handling. It is not dosing guidance, a recommendation, or a claim of safety or efficacy, and it does not account for overfill, dead space, or peptide purity. Nothing here is medical advice. “U-100” means 100 units = 1 mL; confirm your syringe graduation before measuring. See the reconstitution & storage handbook for handling detail.

Frequently asked questions

Answers drawn only from BPC-157's research facts and, where reviewed, its sex-disaggregated evidence. Nothing here is medical advice, dosing, or a claim of safety or efficacy.

What is BPC-157?

BPC-157, also known as Body Protection Compound 157, is a research compound in our healing recovery category. BPC-157 is a synthetic pentadecapeptide widely discussed for tissue healing.

Is BPC-157 studied in women?

BPC-157: of 211 PubMed records, 21 are tagged as including female subjects and 0 carry a sex-analysis tag. We grade this none: no PubMed record for BPC-157 is tagged as including female subjects, so its effects in women are effectively unstudied. That blank is the finding, not a safety signal, and we do not fill it with guesses.

Has BPC-157 been studied during pregnancy or breastfeeding?

Unstudied. No pregnancy or lactation safety data exist. Absence of harm data is not evidence of safety. This is not a safety clearance or a recommendation. Vera, our research chat, deliberately hard-stops on pregnancy, breastfeeding, and trying-to-conceive questions rather than answer them.

What evidence grade does BPC-157 have, and why?

BPC-157 carries evidence grade D. Preclinical / animal evidence only across 211 indexed studies. No human trial data.. Grades are derived from the research record, never hand-assigned; see how grades work.

Is there a female-specific dose for BPC-157?

No. A female-specific dose for BPC-157 is not established, and this site does not provide dosing or medical advice. Any figures we show describe what published research used, not a recommendation. Decide anything about use with a qualified clinician.

How is BPC-157 administered in research?

In the published literature, BPC-157 is administered via subcutaneous, oral, intramuscular. Reported dose ranges on the Dosing tab describe what studies used for laboratory research, not a protocol for people. We don't provide dosing.

What side effects have been reported for BPC-157?

Effects reported in the research literature include insufficient human data to characterize. Sex-specific incidence has not been separately analysed in the available records, so these are not broken out for women.

What is the CAS number for BPC-157?

The CAS registry number for BPC-157 is 137525-51-0. It is also referred to as Body Protection Compound 157, Bepecin. Use it to confirm identity against a Certificate of Analysis.

How should BPC-157 be stored and handled?

BPC-157 sold for research is supplied as a lyophilized (freeze-dried) powder. Lyophilized peptides are generally kept cold and dry, at roughly -20°C for longer-term storage and 2-8°C short-term, protected from light. Once reconstituted they are typically refrigerated and used within a short window, avoiding repeated freeze-thaw cycles. This is general laboratory handling for research use only, not a directive for human use. Always follow the handling and purity details on the product's Certificate of Analysis.

Where can I buy BPC-157 for research?

For laboratory research use, BPC-157 is available from our research-use partner, Aurevena Research. Applying code research15 takes 15% off. We may earn a commission when you purchase through this link, at no extra cost to you. Products are for laboratory research use only.

Buy BPC-157 at Aurevena Research
Research-use supplier: BPC-157 is available from our research-use vendor for laboratory use. Code research15 for 15% off, applied automatically at checkout. We may earn a commission when you purchase through this link, at no extra cost to you. Products are for laboratory research use only.
Buy now →

Citations (PMID)

34064434 · 31500204

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Educational information for laboratory and research use only. Not medical advice, a recommendation, or a claim of safety or efficacy; no personal dosing. “Unstudied” means no qualifying study was found, not that a compound is safe or unsafe.