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Selank

TP-7
Cognitive · CAS 129954-34-3
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Category
Cognitive
Evidence grade
C
PubMed records
125
Female-tagged
26
Sex-analysis
0
CAS
129954-34-3
C
Evidence grade C, Early human data only (Phase 1 / small-n) across 125 indexed studies. How grades work →
Female evidence: None
Selank: of 125 PubMed records, 26 are tagged as including female subjects and 0 carry a sex-analysis tag.Counts reflect PubMed records as of 2026-07-17. “Female” uses the Female MeSH filter and “sex-analysis” the Sex Factors MeSH filter, automated proxies pending manual study-level review. Methodology →

Overview

Selank is a synthetic heptapeptide analog of the immunomodulatory peptide tuftsin, developed as a stabilized research material for neuropeptide and behavioral studies. Its short, tuftsin-derived structure gives it a research-friendly profile for work in cognition and anxiety-related models.

In vitro and in preclinical systems, Selank has been studied for its influence on GABAergic signaling, brain-derived neurotrophic factor (BDNF) expression, monoamine balance, and enkephalin-degradation pathways. Investigators designing anxiolytic and cognition-related research have used it as a research material, frequently alongside related peptides such as Semax. Human data with Selank remains limited.

What makes Selank a useful entry for a cognitive catalog is the breadth of neuropeptide pathways it engages while remaining a compact, well-characterized tool compound. Whether these mechanisms translate to female physiology remains an open research question; our evidence review tracks how many of the underlying studies included women.

Summary

Selank is a synthetic tuftsin-analog heptapeptide studied in neuropeptide and behavioral research. Human data is limited and did not analyze results by sex.

Evidence in women

Menstrual cycle
Unstudied
No menstrual cycle interaction data.
Pregnancy & lactation
Unstudied
No pregnancy or lactation safety data.
Hormonal interactions
Unstudied
No hormonal interaction data.
Perimenopause & menopause
Unstudied
No data in perimenopausal or menopausal populations.
Sex differences
Unstudied
In the indexed literature, many studies included female subjects and none reported sex-stratified outcomes.

Mechanism

Studied for influence on GABAergic signaling, BDNF expression, and enkephalin-degradation pathways in anxiolytic and cognition research models.

Reported dosing & routes

◐

We don't give dosing or medical advice. The figures below describe what was used in published research, not a recommendation. Decide with your clinician.

Reported range (literature)Reported in early studies; no established therapeutic dose in most jurisdictions.
Routesintranasal
Female-specific dosingNot established

Contraindications: not established

Side effects

Reported in the research literature. Sex-specific incidence has not been separately analysed in the available records.

limited human safety data

Selank reconstitution calculator

Enter this vial's amount, the bacteriostatic water you add, and a target amount to get the concentration and the U-100 syringe units to draw. Handling arithmetic for research use, not a dose recommendation.

Reconstitution

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Draw for Selank

5
units on a U-100 insulin syringe
020406080100
U-100 insulin syringe — 1 mL = 100 units
That's 0.05 mL drawn to the 5-unit mark.
Concentration5 mg/mL (5,000 mcg/mL)
Volume to draw0.05 mL
Doses per vial40

Reference chart at 5 mg/mL

Target amountVolume (mL)U-100 units
100 mcg0.02 mL2
250 mcg0.05 mL5
500 mcg0.1 mL10
750 mcg0.15 mL15
1000 mcg0.2 mL20

Research-use arithmetic only. This tool converts a vial amount, diluent volume, and a target amount into a concentration and syringe draw for laboratory handling. It is not dosing guidance, a recommendation, or a claim of safety or efficacy, and it does not account for overfill, dead space, or peptide purity. Nothing here is medical advice. “U-100” means 100 units = 1 mL; confirm your syringe graduation before measuring. See the reconstitution & storage handbook for handling detail.

Frequently asked questions

Answers drawn only from Selank's research facts and, where reviewed, its sex-disaggregated evidence. Nothing here is medical advice, dosing, or a claim of safety or efficacy.

What is Selank?

Selank, also known as TP-7, is a research compound in our cognitive category. Selank is a synthetic tuftsin-analog heptapeptide studied in neuropeptide and behavioral research.

Is Selank studied in women?

Selank: of 125 PubMed records, 26 are tagged as including female subjects and 0 carry a sex-analysis tag. We grade this none: no PubMed record for Selank is tagged as including female subjects, so its effects in women are effectively unstudied. That blank is the finding, not a safety signal, and we do not fill it with guesses.

Has Selank been studied during pregnancy or breastfeeding?

Unstudied. No pregnancy or lactation safety data. This is not a safety clearance or a recommendation. Vera, our research chat, deliberately hard-stops on pregnancy, breastfeeding, and trying-to-conceive questions rather than answer them.

What evidence grade does Selank have, and why?

Selank carries evidence grade C. Early human data only (Phase 1 / small-n) across 125 indexed studies.. Grades are derived from the research record, never hand-assigned; see how grades work.

Is there a female-specific dose for Selank?

No. A female-specific dose for Selank is not established, and this site does not provide dosing or medical advice. Any figures we show describe what published research used, not a recommendation. Decide anything about use with a qualified clinician.

How is Selank administered in research?

In the published literature, Selank is administered via intranasal. Reported dose ranges on the Dosing tab describe what studies used for laboratory research, not a protocol for people. We don't provide dosing.

What side effects have been reported for Selank?

Effects reported in the research literature include limited human safety data. Sex-specific incidence has not been separately analysed in the available records, so these are not broken out for women.

What is the CAS number for Selank?

The CAS registry number for Selank is 129954-34-3. It is also referred to as TP-7, tuftsin analog. Use it to confirm identity against a Certificate of Analysis.

How should Selank be stored and handled?

Selank sold for research is supplied as a lyophilized (freeze-dried) powder. Lyophilized peptides are generally kept cold and dry, at roughly -20°C for longer-term storage and 2-8°C short-term, protected from light. Once reconstituted they are typically refrigerated and used within a short window, avoiding repeated freeze-thaw cycles. This is general laboratory handling for research use only, not a directive for human use. Always follow the handling and purity details on the product's Certificate of Analysis.

Where can I buy Selank for research?

Selank is not currently listed by our research-use partner, Aurevena Research, but their catalog carries related compounds. Code research15 applies 15% off. We may earn a commission when you purchase through this link, at no extra cost to you. Products are for laboratory research use only.

Browse the Aurevena catalog
Research-use supplier: Selank isn't currently listed by our research-use vendor. Their catalog carries related compounds. Code research15 for 15% off, applied automatically at checkout. We may earn a commission when you purchase through this link, at no extra cost to you. Products are for laboratory research use only.
Browse the catalog →

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Educational information for laboratory and research use only. Not medical advice, a recommendation, or a claim of safety or efficacy; no personal dosing. “Unstudied” means no qualifying study was found, not that a compound is safe or unsafe.